Article
beta-catenin gene mutation in invasive ductal breast cancer.
Journal of B.U.ON. : official journal of the Balkan Union of Oncology - 1 Jan 2000
Kizildag S, Zengel B, Vardar E, Sakizli M
Abstract excerpt
PURPOSE: Aberrant accumulation of beta-catenin plays an important role in a variety of human neoplasms. In this study we analyzed the somatic mutations of the beta-catenin gene and the immunohistochemical localization of beta-catenin and cyclin D1 in invasive ductal breast cancer. MATERIALS AND METHODS: We investigated 65 human invasive ductal breast cancer samples for somatic mutations in the exons 3, 4, 5 and 6...
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