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Expression analysis of E-cadherin, Slug and GSK3β in invasive ductal carcinoma of breast

14 Sept 2009

Abstract excerpt

BACKGROUND: Cancer progression is linked to a partially dedifferentiated epithelial cell phenotype. The signaling pathways Wnt, Hedgehog, TGF-beta and Notch have been implicated in experimental and developmental epithelial mesenchymal transition (EMT). Recent findings from our laboratory confirm that active Wnt/beta-catenin signaling is critically involved in invasive ductal carcinomas (IDCs) of breast. METHODS:...

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PMID: 19751508
DOI: 10.1186/1471-2407-9-325

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