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Article

Frequent beta-catenin overexpression without exon 3 mutation in cutaneous lymphomas.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Oct 2004

Bellei Barbara, Pacchiarotti Alberto, Perez Marie, Faraggiana Tullio

Abstract excerpt

Beta-catenin is a ubiquitously cytoplasmic protein that has a critical role in embryonic development and mature tissue homeostasis through its effects on E-cadherin-mediated cell adhesion and Wnt-dependent signal transduction. Mutations that alter specific beta-catenin residues important for GSK-3beta phosphorylation, or increase the half-life of the protein, were identified in human cancer. However, the role of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15195109
DOI: 10.1038/modpathol.3800181

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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