Article
Mating in parents of type 1 diabetes families as a function of the HLA DR-DQ haplotype.
Diabetes, obesity & metabolism - 1 Feb 2009
Kahles H, Kordonouri O, Ramos Lopez E, Walter M, Rosinger S, Boehm B O, Badenhoop K, Seidl C, Ziegler A
Abstract excerpt
AIM: The Major Histocompatibility Complex (MHC) region on chromosome 6p21 (IDDM1) contributes about half of the familial clustering of type 1 diabetes (T1D). Several studies have revealed that highly polymorphic genes within the MHC may associate with the mating choice. Our study should determine whether a specific mating effect is detectable in T1D families as a function of human leucocyte antigen (HLA) DR-DQ,...
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