Article
Age and sex based genetic locus heterogeneity in type 1 diabetes.
Journal of medical genetics - 1 Mar 2000
Paterson A D, Petronis A
Abstract excerpt
BACKGROUND: Two genome scans for susceptibility loci for type 1 diabetes using large collections of families have recently been reported. Apart from strong linkage in both studies of the HLA region on chromosome 6p, clear consistent evidence for linkage was not observed at any other loci. One possible explanation for this is a high degree of locus heterogeneity in type 1 diabetes, and we hypothesised that the sex...
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