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Article

AZD2184: a radioligand for sensitive detection of beta-amyloid deposits.

Journal of neurochemistry - 1 Mar 2009

Johnson Allan E, Jeppsson Fredrik, Sandell Johan, Wensbo David, Neelissen Jan A M, Juréus Anders, Ström Peter, Norman Henrietta, Farde Lars, Svensson Samuel P S

Abstract excerpt

The presence of beta-amyloid plaques in brain is a hallmark of Alzheimer's disease (AD) and serves as a biomarker for confirmation of diagnosis postmortem. Positron emission tomography (PET) radioligands such as Pittsburgh compound B ([(11)C]-2-(3-fluoro-4-methylamino-phenyl)-benzothiazol-6-ol) (PIB) binds selectively to beta-amyloid and are promising new tools supporting the clinical diagnoses of AD. In...

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Source

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PMID: 19141073
DOI: 10.1111/j.1471-4159.2008.05861.x

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APP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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