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Article

Fluorescent indolizine derivative YI-13 detects amyloid-β monomers, dimers, and plaques in the brain of 5XFAD Alzheimer transgenic mouse model.

PloS one - 1 Jan 2020

Kim DaWon, Lee Jeong Hwa, Kim Hye Yun, Shin Jisu, Kim Kyeonghwan, Lee Sejin, Park Jinwoo, Kim JinIkyon, Kim YoungSoo

Abstract excerpt

Alzheimer disease (AD) is a neurodegenerative disorder characterized by the aberrant production and accumulation of amyloid-β (Aβ) peptides in the brain. Accumulated Aβ in soluble oligomer and insoluble plaque forms are considered to be a pathological culprit and biomarker of the disorder. Here, we report a fluorescent universal Aβ-indicator YI-13,...

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Identifiers

PMID: 33362250
DOI: 10.1371/journal.pone.0243041
PMCID: PMC7757811

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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