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Article

K114 inhibits A-beta aggregation and inflammation in vitro and in vivo in AD/Tg mice.

Current Alzheimer research - 1 Mar 2014

Zhang Yi-Hong, Mann Dushyant, Raymick James, Sarkar Sumit, Paule Merle G, Lahiri Debomoy K, Dumas Melanie, Bell-Cohen Ashlee, Schmued Larry C

Abstract excerpt

Alzheimer's disease (AD) is the most common age related human neurodegenerative disorder. The major histopathological characteristics of the AD brain are extracellular amyloid-beta (Aβ) peptide loaded plaques and intraneuronal neurofibrillary tangles made of phosphorylated tau proteins. Amyloid plaques consist primarily of aggregated Aβ1-42 and Aβ1-40 peptides. The aim of our current study was to test novel...

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Source

Identifiers

PMID: 24552157
DOI: 10.2174/1567205011666140220125324

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GFAP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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