Article

High-contrast in-vivo imaging of tau pathologies in Alzheimer’s and non-Alzheimer’s disease tauopathies

2020-03-11

Abstract excerpt

<h4>SUMMRAY</h4> A panel of radiochemicals has enabled in-vivo positron emission tomography (PET) of tau pathologies in Alzheimer’s disease (AD), while sensitive detection of frontotemporal lobar degeneration (FTLD) tau inclusions has been unsuccessful. Here, we generated an imaging probe, PM-PBB3, for capturing diverse tau deposits. In-vitro assays demonstrated the reactivity of this compound with tau pathologies...

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Literature Corpus work: c9522652-02e5-5698-9e03-e5134ce4d7b0
DOI: 10.1101/2020.03.05.20028407

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