Article
Ethnic variability in human leukocyte antigen-E haplotypes.
Tissue antigens - 1 Jan 2009
Antoun A, Jobson S, Cook M, Moss P, Briggs D
Abstract excerpt
Human leukocyte antigen-E (HLA-E) is an important nonclassical major histocompatibility complex (MHC) class I (Ib) molecule that acts as the ligand for NKG2A/B/C receptors expressed on natural killer (NK) cells and T cells. Unlike the classical class I molecules, HLA-E is highly conserved in evolution and the biological significance of polymorphism is therefore unclear. Our aim was to investigate the polymorphism...
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