Article
HLA-E polymorphisms in an Afro-descendant Southern Brazilian population.
Human immunology - 1 Feb 2013
Carvalho dos Santos Luana, Tureck Luciane Viater, Wowk Pryscilla Fanini, Mattar Sibelle Botogosque, Gelmini Georgia Fernanda, Magalhães João Carlos Marques, Bicalho Maria da Graça, Roxo Valéria Maria Munhoz Sperandio
Abstract excerpt
HLA-E is a non-classical I (Ib) gene which has limited polymorphism and low levels of tissue expression. Currently, 11 alleles are described in the literature with only three protein products. In the present study we investigated HLA-E gene variations at exons 2 and 3 and calculated allele, genotype and haplotype frequencies in a sample of 152 individuals who reported themselves as being Afro-descendants and who...
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