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Article

Worldwide HLA-E nucleotide and haplotype variability reveals a conserved gene for coding and 3' untranslated regions.

Tissue antigens - 1 Feb 2014

Felício L P, Porto I O P, Mendes-Junior C T, Veiga-Castelli L C, Santos K E, Vianello-Brondani R P, Sabbagh A, Moreau P, Donadi E A, Castelli E C

Abstract excerpt

The human leukocyte antigen-E (HLA-E) locus is a human major histocompatibility complex (MHC) gene associated with immune-modulation and suppression of the immune response by the interaction with specific natural killer (NK) and T cell receptors (TCRs). It is considered one of the most conserved genes of the human MHC; however, this low nucleotide variability seems to be a consequence of the scarce number of...

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PMID: 24400773
DOI: 10.1111/tan.12283

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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