Article
The impact of HLA-E polymorphisms in graft-versus-host disease following HLA-E matched allogeneic hematopoietic stem cell transplantation.
Iranian journal of allergy, asthma, and immunology - 1 Mar 2012
Hosseini Ehteramolsadat, Schwarer Anthony P, Ghasemzadeh Mehran
Abstract excerpt
The non-classical MHC class-I mainly involves in the regulation of innate immune responses where HLA-E plays a significant role in the cell identification by natural killer cells. HLA-E is a main regulatory ligand for natural killer cells and given the importance of these effector cells in hematopoietic stem cell transplantation, we investigated the effect of HLA-E polymorphisms on post-hematopoietic stem cell...
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