Article
New insights in HLA-E polymorphism by refined analysis of the full-length gene.
HLA - 1 Mar 2017
Olieslagers T I, Voorter C E M, Groeneweg M, Xu Y, Wieten L, Tilanus M G J
Abstract excerpt
BACKGROUND: Human leukocyte antigen (HLA)-E is a non-classical HLA class I molecule that plays a role in both the innate and the adaptive immune response through interaction with receptors on natural killer- and T-cells. The HLA-E gene is characterized by limited polymorphism compared with the classical HLA loci on chromosome 6. At the start of this study, only 13 variable sites had been identified (IPD-IMGT/HLA...
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