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Article

HLA-E diversity unfolded: Identification and characterization of 170 novel HLA-E alleles.

HLA - 1 May 2021

Paech Christin, Albrecht Viviane, Putke Kathrin, Schöfl Gerhard, Schöne Bianca, Schmidt Alexander H, Lange Vinzenz, Klussmeier Anja

Abstract excerpt

HLA-E is a member of the nonclassical HLA class Ib genes. Even though it is structurally highly similar to the classical HLA class Ia genes, it is less diverse and only 45 alleles and 12 proteins were known in December 2019 (IPD-IMGT/HLA, release 3.38.0). Since 2017, we have genotyped over 3 million voluntary stem cell donors for HLA-E by sequencing the most relevant allele-determining bases of exons 2 and 3. As...

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Identifiers

PMID: 33527770
DOI: 10.1111/tan.14195
PMCID: PMC8247977

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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