Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphism at the HLA-E locus predates most HLA-A and -B polymorphism.

Human immunology - 1 Mar 1992

Geraghty D E, Stockschleader M, Ishitani A, Hansen J A

Abstract excerpt

The extensive polymorphism of the classic class I antigens has been well described. In contrast, the nonclassic HLA antigens are distinguished by their low polymorphism. We examine here the HLA polymorphism of the HLA-E locus by examining the DNA sequence of cDNA from nine ethnically diverse individuals. From this analysis, we show that there is no polymorphism in the regions including exon 1 and from exon 4 to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Amino Acid Sequence
Share to Base Sequence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chromosome Mapping

Share to HLA Antigens

Share to HLA-B Antigens

Share to Molecular Sequence Data

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 1618657
DOI: 10.1016/0198-8859(92)90069-y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphism at the HLA-E locus predates most HLA-A and -B polymorphism.PMID 1618657Read ↗

An In-Depth Review of the Genetics of the Non-Classical HLA Class I Gene HLA-E and Its Effects on Haematopoietic Cell Transplant Outcomes.Semantic proximity Read ↗

HLA-E, HLA-F, and HLA-G polymorphism: genomic sequence defines haplotype structure and variation spanning the nonclassical class I genes.Semantic proximity Read ↗

HLA-E allelic variants. Correlating differential expression, peptide affinities, crystal structures, and thermal stabilities.Semantic proximity Read ↗

Ethnic variability in human leukocyte antigen-E haplotypes.Semantic proximity Read ↗

Non-classical HLA-E gene variability in Brazilians: a nearly invariable locus surrounded by the most variable genes in the human genome.Semantic proximity Read ↗

New insights in HLA-E polymorphism by refined analysis of the full-length gene.Semantic proximity Read ↗

HLA-E diversity unfolded: Identification and characterization of 170 novel HLA-E alleles.Semantic proximity Read ↗

Worldwide HLA-E nucleotide and haplotype variability reveals a conserved gene for coding and 3' untranslated regions.Semantic proximity Read ↗

Full-length gene polymorphism of the non-classical HLA-E in Estonian individuals.Semantic proximity Read ↗

Population genetic studies of HLA-E: evidence for selection.Semantic proximity Read ↗

Distinctive polymorphism at the HLA-C locus: implications for the expression of HLA-C.Semantic proximity Read ↗

A novel HLA-E allele, E*01:03:05, identified in two Brazilian individuals.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.