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Article

[Creation of valuable antibodies by an in vitro antibody generation system using a hypermutating B cell line].

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan - 1 Jan 2009

Kanayama Naoki, Todo Kagefumi, Magari Masaki, Ohmori Hitoshi

Abstract excerpt

Monoclonal antibodies (mAb) have recently proven to be excellent biopharmaceutical agents. The generation of hybridomas from antigen-stimulated B cells has been a key technology for obtaining mAbs; however, it is a laborious and time-consuming process, and sometimes mAbs for molecules conserved between species are difficult to obtain because of immunological tolerance. Thus, it is of great importance to develop...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19122431
DOI: 10.1248/yakushi.129.11

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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