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Article

PTPN22 C1858T polymorphism and the outcome of hepatitis C virus infection.

Viral immunology - 1 Dec 2008

Montes-Cano M A, García-Lozano J R, Aguilar-Reina J, Romero-Gómez M, Barroso N, Nuñez-Roldán A, Martín J, González-Escribano M F

Abstract excerpt

The outcome of chronic hepatitis C virus infection varies, depending on viral and host factors. Those mechanisms involved in the control of the innate and adaptive response could have an influence on the outcome of infection. The PTPN22 gene encodes an intracellular lymphoid-specific phosphatase (Lyp) with a lymphocyte activating downregulatory effect. A single-nucleotide polymorphism (SNP) C1858T located on this...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19115939
DOI: 10.1089/vim.2008.0040

Genes

PTPN22

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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