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Article

Association of PTPN22 gene polymorphisms with chronic hepatitis B virus infection in Chinese Han population.

Human immunology - 1 Oct 2015

Li Fang, Li Na, Zhu Qianqian, Zhou Zhihua, Zhang Pingping, Yang Cuiling, Han Qunying, Lv Yi, Wei Ping, Liu Zhengwen

Abstract excerpt

Lymphoid protein tyrosine phosphatase encoded by protein tyrosine phosphatase non-receptor 22 (PTPN22) gene plays an important regulatory role in T- and B-cell activation. This study investigated PTPN22 -1123G/C and intron 16 T/C polymorphisms in 372 patients with chronic hepatitis B virus (HBV) infection, 72 HBV infection resolvers and 273 healthy controls. Genotypic association tests between groups assuming...

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Source

Identifiers

PMID: 26429315
DOI: 10.1016/j.humimm.2015.09.030

Genes

PTPN22

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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