Article
Antigen-processing polymorphisms in chronic hepatitis C infection.
Experimental and clinical immunogenetics - 1 Jan 1996
Höhler T, Gerken G, Schneider P M, Meyer zum Büschenfelde K H, Rittner C
Abstract excerpt
BACKGROUND: Cytotoxic T cell (CTL) responses may influence the course of a hepatitis C infection. CTL recognize viral peptides on HLA class I molecules. Antigenic peptides for class I presentation are generated by proteasomes and transported into the endoplasmic reticulum by the TAP proteins. It...
Topics
- ATP Binding Cassette Transporter, Subfamily B, Member 2
- ATP Binding Cassette Transporter, Subfamily B, Member 3
- ATP-Binding Cassette Transporters
- Alleles
- Amino Acid Sequence
- Antigen Presentation
- Chronic Disease
- Cysteine Endopeptidases
- Hepatitis C
- Humans
- Major Histocompatibility Complex
- Polymorphism, Genetic
- Proteins