Article
PTPN22 1858C>T gene polymorphism in patients with SLE: association with serological and clinical results.
Molecular biology reports - 1 Sept 2014
Ostanek Lidia, Ostanek-Pańka Magdalena, Bobrowska-Snarska Danuta, Bińczak-Kuleta Agnieszka, Fischer Katarzyna, Kaczmarczyk Mariusz, Ciechanowicz Andrzej, Brzosko Marek
Abstract excerpt
To assess the association between PTPN22 1858C>T gene polymorphism and susceptibility to, and clinical presentation of, systemic lupus erythematosus (SLE). Our study included 135 SLE patients (120 women and 15 men; mean age 45.1 years; mean course of disease from 0.5 to 31 years) and 201 healthy subjects. The PTPN22 1858C>T gene polymorphism was genotyped by polymerase chain reaction restriction fragment length...
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