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Article

The PTPN22 R620W polymorphism is associated with severe bacterial infections after human leukocyte antigen geno-identical haematopoietic stem-cell transplantations.

Transplantation - 27 Jun 2008

Azarian Mariam, Busson Marc, Rocha Vanderson, Ribaud Patricia, Peffault de Latour Regis, Bleux Hélène, Lepage Virginia, Charron Dominique, Toubert Antoine, Socié Gérard, Loiseau Pascale

Abstract excerpt

PTPN22 is a negative regulator of T-cell activation. The C1858T PTPN22 polymorphism has been associated with autoimmune diseases. The role of PTPN22 in immune response and autoimmune diseases suggested that PTPN22 polymorphism could impact outcome of allogeneic hematopoietic stem-cell transplanta...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Protein Tyrosine Phosphatase, Non-Receptor Type 22

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Source

Identifiers

PMID: 18580482
DOI: 10.1097/TP.0b013e31817729c4

Genes

PTPN22

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18580482-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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The PTPN22 R620W polymorphism is associated with severe bacterial infections after human leukocyte antigen geno-identical haematopoietic stem-cell transplantations.PMID 18580482Read ↗

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