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Article

PTPN22 C1858T polymorphism and human brucellosis.

Scandinavian journal of infectious diseases - 1 Jan 2009

Bravo Maria Jose, Colmenero Juan Dios, Queipo-Ortuño Maria Isabel, Morata Pilar, Orozco Gisela, Martin Javier, Alonso Antonio, Caballero Abelardo

Abstract excerpt

The PTPN22 gene encodes for an intracellular lymphoid-specific phosphatase (Lyp) that has a negative regulatory effect on T-cell activation. The minor allele of the single nucleotide polymorphism (SNP) in the PTPN22 gene encoding the Lyp-tyrosine phosphatase has been associated with multiple auto...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Protein Tyrosine Phosphatase, Non-Receptor Type 22

Source

Identifiers

PMID: 19107641
DOI: 10.1080/00365540802641864

Genes

PTPN22

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19107641-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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