Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Fly-TILL: reverse genetics using a living point mutation resource.

Fly - 1 Jan 2000

Cooper Jennifer L, Till Bradley J, Henikoff Steven

Abstract excerpt

Mutagenesis with ethylmethanesulfonate (EMS) has been the standard for traditional genetic screens, and in recent years has been applied to reverse genetics. However, reverse-genetic strategies require maintaining a viable germline library so that mutations that are discovered can subsequently be...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Crosses, Genetic
Share to DNA Mutational Analysis
Share to Drosophila melanogaster

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Ethyl Methanesulfonate

Share to Genes, Insect

Share to Genetic Techniques

Share to Genetic Variation

Share to Point Mutation

Source

Identifiers

PMID: 19098435
DOI: 10.4161/fly.7366

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19098435-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fly-TILL: reverse genetics using a living point mutation resource.PMID 19098435Read ↗

Retention of induced mutations in a Drosophila reverse-genetic resource.Semantic proximity Read ↗

Target-selected mutant screen by TILLING in Drosophila.Semantic proximity Read ↗

EMS screens : from mutagenesis to screening and mapping.Semantic proximity Read ↗

Discovery of induced point mutations in maize genes by TILLING.Semantic proximity Read ↗

A mutant Brassica napus (canola) population for the identification of new genetic diversity via TILLING and next generation sequencing.Semantic proximity Read ↗

Spectrum of chemically induced mutations from a large-scale reverse-genetic screen in Arabidopsis.Semantic proximity Read ↗

TILLING: practical single-nucleotide mutation discovery.Semantic proximity Read ↗

Large-scale identification of chemically induced mutations in Drosophila melanogaster.Semantic proximity Read ↗

TILLING: The Next Generation.Semantic proximity Read ↗

The Zuker collection: a resource for the analysis of autosomal gene function in Drosophila melanogaster.Semantic proximity Read ↗

Analysis of the genome sequences of three Drosophila melanogaster spontaneous mutation accumulation lines.Semantic proximity Read ↗

Screening Mutants by Single Fly Genomic PCR.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.