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Article

Induction of cytochrome P450 2B6 activity by the herbal medicine baicalin as measured by bupropion hydroxylation.

European journal of clinical pharmacology - 1 Apr 2009

Fan Lan, Wang Jin-Chao, Jiang Feng, Tan Zhi-Rong, Chen Yao, Li Qing, Zhang Wei, Wang Guo, Lei He-Ping, Hu Dong-Li, Wang Dan, Zhou Hong-Hao

Abstract excerpt

PURPOSE: This study investigated the effect of the herbal medicine baicalin on bupropion hydroxylation, a probe reaction for CYP2B6 activity related to different CYP2B6 genotype groups. METHOD: Seventeen healthy male volunteers (6 CYP2B6*1/*1, 6 CYP2B6*1/*6, and 5 CYP2B6*6/*6) received orally administered bupropion alone and during daily treatment with baicalin. Blood samples were taken up to 72 h after each...

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Identifiers

PMID: 19066872
DOI: 10.1007/s00228-008-0594-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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