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Article

Human ether-a-go-go related gene (hERG) K+ channels: function and dysfunction.

Progress in biophysics and molecular biology - 1 Jan 2000

Perrin Mark J, Subbiah Rajesh N, Vandenberg Jamie I, Hill Adam P

Abstract excerpt

The human Ether-a-go-go Related Gene (hERG) potassium channel plays a central role in regulating cardiac excitability and maintenance of normal cardiac rhythm. Mutations in hERG cause a third of all cases of congenital long QT syndrome, a disorder of cardiac repolarisation characterised by prolongation of the QT interval on the surface electrocardiogram, abnormal T waves, and a risk of sudden cardiac death due to...

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Identifiers

PMID: 19027781
DOI: 10.1016/j.pbiomolbio.2008.10.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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