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Article

Current pharmacogenomic studies on hERG potassium channels.

Trends in molecular medicine - 1 Apr 2013

He Fa-Zhong, McLeod Howard L, Zhang Wei

Abstract excerpt

Genetic polymorphisms in human ether-a-go-go-related gene (hERG) potassium channels are associated with many complex diseases and sensitivity to channel-related drugs. Genotypes may underlie different sensitivities to the same drug, and different drugs selectively repair the functional deficits caused by individual mutations. In fact, not all drugs that block hERG function have adverse effects as previously...

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Source

Identifiers

PMID: 23369369
DOI: 10.1016/j.molmed.2012.12.006

Genes

KCNH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Current pharmacogenomic studies on hERG potassium channels.PMID 23369369Read ↗

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