Article
HERG, a human inward rectifier in the voltage-gated potassium channel family.
Science (New York, N.Y.) - 7 Jul 1995
Trudeau M C, Warmke J W, Ganetzky B, Robertson G A
Abstract excerpt
In contrast to other members of the Eag family of voltage-gated, outwardly rectifying potassium channels, the human eag-related gene (HERG) has now been shown to encode an inwardly rectifying potassium channel. The properties of HERG channels are consistent with the gating properties of Eag-related and other outwardly rectifying, S4-containing potassium channels, but with the addition of an inactivation mechanism...
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