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Article

Long QT syndrome: cellular basis and arrhythmia mechanism in LQT2.

Journal of cardiovascular electrophysiology - 1 Dec 2000

January C T, Gong Q, Zhou Z

Abstract excerpt

LQT2 is one form of the congenital long QT syndrome. It results from mutations in the human ether-a-go-go-related gene (HERG), and more than 80 mutations, usually causing single amino acid substitutions in the HERG protein, are known. HERG encodes the ion channel pore-forming subunit protein for the rapidly activating delayed rectifier K+ channel (I(Kr)) in the heart. This review summarizes current findings about...

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Identifiers

PMID: 11196567
DOI: 10.1046/j.1540-8167.2000.01413.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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