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Article

Lack of association between sCTLA-4 levels in human plasma and common CTLA-4 polymorphisms.

Journal of negative results in biomedicine - 12 Nov 2008

Berry Andrew, Tector Matt, Oaks Martin K

Abstract excerpt

BACKGROUND: Cytotoxic T lymphocyte antigen-4 (CTLA-4) is an important downregulatory molecule expressed on both T and B lymphocytes. Numerous population genetics studies have documented significant associations between autoimmune diseases and single nucleotide polymorphisms (SNPs) within and around the CTLA-4 region of chromosome 2 in man. Furthermore, circulating levels of a soluble form of CTLA-4 (sCTLA-4) have...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19014504
DOI: 10.1186/1477-5751-7-8
PMCID: PMC2596078

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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