Article
No evidence for allelic association of a human CTLA-4 promoter polymorphism with autoimmune thyroid disease in either population-based case-control or family-based studies.
Clinical endocrinology - 1 Sept 1998
Heward J M, Allahabadia A, Carr-Smith J, Daykin J, Cockram C S, Gordon C, Barnett A H, Franklyn J A, Gough S C
Abstract excerpt
OBJECTIVE: The cytotoxic T lymphocyte associated-4 (CTLA-4) gene is a candidate for T-cell mediated autoimmune disease and polymorphism has been reported to be associated with both type 1 diabetes and autoimmune thyroid disease. A previously unreported polymorphism of the promoter region of the h...
Topics
- Abatacept
- Alleles
- Antigens, CD
- Antigens, Differentiation
- Autoimmune Diseases
- CTLA-4 Antigen
- Case-Control Studies
- China
- Genotype
- Graves Disease
- Hong Kong
- Humans
- Hypothyroidism
- Immunoconjugates