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Article

CTLA-4 gene polymorphisms and natural soluble CTLA-4 protein in psoriasis vulgaris.

International journal of immunogenetics - 1 Jun 2006

Luszczek W, Kubicka W, Jasek M, Baran E, Cisło M, Nockowski P, Luczywo-Rudy M, Wiśniewski A, Nowak I, Kuśnierczyk P

Abstract excerpt

CTLA-4 molecule is an important inhibitor of T-lymphocyte activation. Several single nucleotide polymorphisms (SNPs) in the CTLA-4 gene were found, and their associations with many human diseases were described. So far, however, such studies have not been performed in psoriasis vulgaris in Caucasoids. Therefore, we examined the distribution of three CTLA-4 SNPs: -1147C/T, -318C/T and +49 A/G in 116 patients with...

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Identifiers

PMID: 16712655
DOI: 10.1111/j.1744-313X.2006.00600.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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