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Article

Escherichia coli tmRNA lacking pseudoknot 1 tags truncated proteins in vivo and in vitro.

RNA (New York, N.Y.) - 1 Jan 2009

Wower Iwona K, Zwieb Christian, Wower Jacek

Abstract excerpt

Transfer-messenger RNA (tmRNA) and protein SmpB facilitate trans-translation, a quality-control process that tags truncated proteins with short peptides recognized by a number of proteases and recycles ribosomes stalled at the 3' end of mRNA templates lacking stop codons. The tmRNA molecule is a hybrid of tRNA- and mRNA-like domains that are usually connected by four pseudoknots (pk1-pk4). Replacement of pk1 with...

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Identifiers

PMID: 19001120
DOI: 10.1261/rna.1192409
PMCID: PMC2612775

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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