Article
Bifunctional transfer-messenger RNA.
Biochimie - 1 Nov 2011
Keiler Kenneth C, Ramadoss Nitya S
Abstract excerpt
Transfer-messenger RNA (tmRNA) is a bifunctional RNA that has properties of a tRNA and an mRNA. tmRNA uses these two functions to release ribosomes stalled during translation and target the nascent polypeptides for degradation. This concerted reaction, known as trans-translation, contributes to translational quality control and regulation of gene expression in bacteria. tmRNA is conserved throughout bacteria, and...
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