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Article

Functional and structural analysis of a pseudoknot upstream of the tag-encoded sequence in E. coli tmRNA.

Journal of molecular biology - 26 Feb 1999

Nameki N, Felden B, Atkins J F, Gesteland R F, Himeno H, Muto A

Abstract excerpt

Escherichia coli tmRNA (transfer-messenger RNA) facilitates a trans-translation reaction in which a stalled ribosome on a terminatorless mRNA switches to an internal coding sequence in tmRNA, resulting in the addition of an 11 amino acid residue tag to the truncated protein that is a signal for degradation and in recycling of the stalled ribosome. A tmRNA secondary structure model with a partial tRNA-like...

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Source

Identifiers

PMID: 10024447
DOI: 10.1006/jmbi.1998.2487

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Functional and structural analysis of a pseudoknot upstream of the tag-encoded sequence in E. coli tmRNA.PMID 10024447Read ↗

Genetic analysis of the structure and function of transfer messenger RNA pseudoknot 1.Semantic proximity Read ↗

Escherichia coli tmRNA lacking pseudoknot 1 tags truncated proteins in vivo and in vitro.Semantic proximity Read ↗

An NMR and mutational analysis of an RNA pseudoknot of Escherichia coli tmRNA involved in trans-translation.Semantic proximity Read ↗

Importance of the conserved nucleotides around the tRNA-like structure of Escherichia coli transfer-messenger RNA for protein tagging.Semantic proximity Read ↗

Three of four pseudoknots in tmRNA are interchangeable and are substitutable with single-stranded RNAs.Semantic proximity Read ↗

Transfer-messenger RNA unfolds as it transits the ribosome.Semantic proximity Read ↗

Determinants on tmRNA for initiating efficient and precise trans-translation: some mutations upstream of the tag-encoding sequence of Escherichia coli tmRNA shift the initiation point of trans-translation in vitro.Semantic proximity Read ↗

Requirements for resuming translation in chimeric transfer-messenger RNAs of Escherichia coli and Mycobacterium tuberculosis.Semantic proximity Read ↗

tmRNA determinants required for facilitating nonstop mRNA decay.Semantic proximity Read ↗

A functional interaction of SmpB with tmRNA for determination of the resuming point of trans-translation.Semantic proximity Read ↗

RluA is the major mRNA pseudouridine synthase in <i>Escherichia coli</i>Semantic proximity Read ↗

Local structural and environmental factors define the efficiency of an RNA pseudoknot involved in programmed ribosomal frameshift process.Semantic proximity Read ↗

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