Article
Three of four pseudoknots in tmRNA are interchangeable and are substitutable with single-stranded RNAs.
FEBS letters - 31 Mar 2000
Nameki N, Tadaki T, Himeno H, Muto A
Abstract excerpt
A novel translation, trans-translation, is facilitated by a highly structured RNA molecule, tmRNA. This molecule has two structural domains, a tRNA domain and an mRNA domain, the latter including four pseudoknot structures (PK1 to PK4). Here, we show that replacement of each of these pseudoknots, except PK1, in Escherichia coli tmRNA with a single stranded RNA did not seriously affect the functions as an alanine...
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