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Article

Genotype error detection using Hidden Markov Models of haplotype diversity.

Journal of computational biology : a journal of computational molecular cell biology - 1 Nov 2008

Kennedy Justin, Măndoiu Ion, Paşaniuc Bogdan

Abstract excerpt

The presence of genotyping errors can invalidate statistical tests for linkage and disease association, particularly for methods based on haplotype analysis. Becker et al. have recently proposed a simple likelihood ratio approach for detecting errors in trio genotype data. Under this approach, a SNP genotype is flagged as a potential error if the likelihood associated with the original trio genotype data...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 18973433
DOI: 10.1089/cmb.2007.0133

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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