Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Detection rates for genotyping errors in SNPs using the trio design.

Human heredity - 1 Jan 2002

Geller Frank, Ziegler Andreas

Abstract excerpt

One well-known approach for the analysis of transmission-disequilibrium is the investigation of single nucleotide polymorphisms (SNPs) in trios consisting of an affected child and its parents. Results may be biased by erroneously given genotypes. Various reasons, among them sample swap or wrong pedigree structure, represent a possible source for biased results. As these can be partly ruled out by good study...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genotype
Share to Polymorphism, Single Nucleotide
Share to Research Design

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Selection Bias

Source

Identifiers

PMID: 12626844
DOI: 10.1159/000068836

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Detection rates for genotyping errors in SNPs using the trio design.PMID 12626844Read ↗

An analytic solution to single nucleotide polymorphism error-detection rates in nuclear families: implications for study design.Semantic proximity Read ↗

Genotyping errors: causes, consequences and solutions.Semantic proximity Read ↗

True pedigree errors more frequent than apparent errors for single nucleotide polymorphisms.Semantic proximity Read ↗

Identification of probable genotyping errors by consideration of haplotypes.Semantic proximity Read ↗

Genotype error detection using Hidden Markov Models of haplotype diversity.Semantic proximity Read ↗

Assessing genuine parents-offspring trios for genetic association studies.Semantic proximity Read ↗

Bayesian trio models for association in the presence of genotyping errors.Semantic proximity Read ↗

Using DNA pools for genotyping trios.Semantic proximity Read ↗

Relationship inference from trios of individuals, in the presence of typing error.Semantic proximity Read ↗

Undetected genotyping errors cause apparent overtransmission of common alleles in the transmission/disequilibrium test.Semantic proximity Read ↗

On confidence intervals for genotype relative risks and attributable risks from case parent trio designs for candidate-gene studies.Semantic proximity Read ↗

Using unaffected child trios to test for transmission distortion.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.