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Article

Genotype calling and haplotyping in parent-offspring trios.

Genome research - 1 Jan 2013

Chen Wei, Li Bingshan, Zeng Zhen, Sanna Serena, Sidore Carlo, Busonero Fabio, Kang Hyun Min, Li Yun, Abecasis Gonçalo R

Abstract excerpt

Emerging sequencing technologies allow common and rare variants to be systematically assayed across the human genome in many individuals. In order to improve variant detection and genotype calling, raw sequence data are typically examined across many individuals. Here, we describe a method for genotype calling in settings where sequence data are available for unrelated individuals and parent-offspring trios and...

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Share to Genome, Human
Share to Genotyping Techniques
Share to Haplotypes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Linkage Disequilibrium

Share to Models, Genetic

Share to Pedigree

Share to Polymorphism, Single Nucleotide

Share to Sequence Analysis, DNA

Source

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Identifiers

PMID: 23064751
DOI: 10.1101/gr.142455.112
PMCID: PMC3530674

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