Article
Haplotype frequency estimation in the presence of genotyping errors.
Human heredity - 1 Jan 2003
Zou Guohua, Zhao Hongyu
Abstract excerpt
Several statistical methods have been proposed to estimate haplotype frequencies, either based on unrelated individuals or based on families. These estimates may yield insights on population genetics as well as associations between candidate regions and disease of interest. One limitation of the existing methods is that all these methods make the implicit assumption that there are no genotyping errors. However,...
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