Article
Relationship inference from trios of individuals, in the presence of typing error.
American journal of human genetics - 1 Jan 2002
Sieberts Solveig K, Wijsman Ellen M, Thompson Elizabeth A
Abstract excerpt
Misspecification of relationships and of genotype data can cause problems in linkage analyses based on genome-scan data. Previous reports have focused on pairwise relationships and a simple error model. This article considers the increased information available from the joint analysis of trios of individuals, integrating this analysis with an error model that allows for the most common genotyping errors. Given...
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