Article
GBScleanR: robust genotyping error correction using a hidden Markov model with error pattern recognition.
Genetics - 26 May 2023
Furuta Tomoyuki, Yamamoto Toshio, Ashikari Motoyuki
Abstract excerpt
Reduced-representation sequencing (RRS) provides cost-effective and time-saving genotyping platforms. Despite the outstanding advantage of RRS in throughput, the obtained genotype data usually contain a large number of errors. Several error correction methods employing the hidden Markov model (HMM) have been developed to overcome these issues. These methods assume that markers have a uniform error rate with no...
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