Article
Marker genotyping errors in old data on X-linkage in bipolar illness.
Biological psychiatry - 1 Apr 1991
Gershon E S
Abstract excerpt
Investigations of linkage markers of the X-chromosome colorblindness region in bipolar manic-depressive illness (BP) have yielded inconsistent results, with linkage accepted in some and rejected in other studies. Although genetic heterogeneity has been proposed as the reason for differences, other possibilities exist, including systematic procedural errors. Statistical evidence for linkage between the markers, Xg...
Topics
- Alleles
- Bipolar Disorder
- Color Vision Defects
- Depressive Disorder
- Genetic Linkage
- Genetic Markers
- Genotype
- Humans
- Models, Genetic
- Phenotype
- Reproducibility of Results
- Sex Chromosome Aberrations
