Article
Manic-depressive illness and linkage reanalysis in the Xq27-Xq28 region of chromosome X.
Neuropsychobiology - 1 Jan 1995
Mendelbaum K, Sevy S, Souery D, Papadimitriou G N, De Bruyn A, Raeymaekers P, Van Broeckhoven C, Mendlewicz J
Abstract excerpt
Inconsistent findings in X linkage studies of manic-depressive illness (MDI) have been ascribed to the presence of phenotypic uncertainties (incomplete penetrance), considerable variation in form and severity of MDI, and the likely presence of phenocopies (or false positives). In order to address...
Topics
- Adult
- Bipolar Disorder
- Chromosome Mapping
- Color Vision Defects
- Depressive Disorder
- Factor IX
- Female
- Genetic Linkage
- Genetic Markers
- Glucosephosphate Dehydrogenase Deficiency
- Humans
- Male
- Middle Aged
- Models, Genetic
- Phenotype
- Sex Chromosome Aberrations
- X Chromosome