Article
Progress and pitfalls: bipolar molecular linkage studies.
Journal of affective disorders - 1 Sept 1998
Berrettini W
Abstract excerpt
This paper reviews the history of molecular genetic linkage studies of bipolar disorder. The topic is introduced with a brief discussion of various genetic concepts, including linkage, lod scores and non-parametric statistics. It is emphasized that criteria for declaring linkage must include inde...
Topics
- Bipolar Disorder
- Chromosomes, Human, Pair 11
- Chromosomes, Human, Pair 16
- Chromosomes, Human, Pair 18
- Chromosomes, Human, Pair 21
- Chromosomes, Human, Pair 22
- Chromosomes, Human, Pair 4
- Genetic Linkage
- Genetic Predisposition to Disease
- Humans
- Pedigree
- Reproducibility of Results
- Research Design
- Trinucleotide Repeats
- X Chromosome
