Article
Linkage analysis of bipolar illness with X-chromosome DNA markers: a susceptibility gene in Xq27-q28 cannot be excluded.
American journal of medical genetics - 15 Dec 1994
De bruyn A, Raeymaekers P, Mendelbaum K, Sandkuijl L A, Raes G, Delvenne V, Hirsch D, Staner L, Mendlewicz J, Van Broeckhoven C
Abstract excerpt
Transmission studies have supported the presence of a susceptibility gene for bipolar (BP) illness on the X-chromosome. Initial linkage studies with color blindness (CB), glucose-6-phosphate dehydrogenase (G6PD) deficiency, and the blood coagulation factor IX (F9) have suggested that a gene for B...
Topics
- Adolescent
- Adult
- Age of Onset
- Chromosome Mapping
- Color Vision Defects
- DNA
- Factor IX
- Female
- Genetic Linkage
- Genetic Markers
- Genetic Predisposition to Disease
- Glucosephosphate Dehydrogenase Deficiency
- Humans
- Lod Score
- Male