A meta-analysis of chromosome 18 linkage data for bipolar illness.

doi:10.1002/(SICI)1098-2272(1997)14:6<617::AID-GEPI11>3.0.CO;2-T

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Article

A meta-analysis of chromosome 18 linkage data for bipolar illness.

Genetic epidemiology - 1 Jan 1997

Dorr D A, Rice J P, Armstrong C, Reich T, Blehar M

Abstract excerpt

We find a meta-data set (715 families, up to 1,124 sib pairs) for bipolar illness to have a strong signal in a 10 cM region around D18S40, and excess paternal sharing on the q arm near marker D18S64. We describe a method for meta-analysis of microsatellite marker data using affected sib-pair (ASP...

Topics

Alleles
Bipolar Disorder
Chromosomes, Human, Pair 18
Female
Genetic Linkage
Genotype
Humans
Male
Matched-Pair Analysis
Nuclear Family

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