Article
Genetic polymorphisms in hMTH1, hOGG1 and hMYH and risk of chronic benzene poisoning in a Chinese occupational population.
Toxicology and applied pharmacology - 15 Dec 2008
Wu Fen, Zhang Zhongbin, Wan Junxiang, Gu Shouyong, Liu Weiwei, Jin Xipeng, Xia Zhaolin
Abstract excerpt
Oxidative damage to DNA induced by benzene is an important mechanism of its genotoxicity, which leads to chronic benzene poisoning (CBP). Therefore, genetic variation in DNA repair genes may contribute to susceptibility to CBP in the exposed population. We hypothesized that single nucleotide poly...
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