Article
hOGG1(326), XRCC1(399) and XRCC3(241) polymorphisms influence micronucleus frequencies in human lymphocytes in vivo.
Mutagenesis - 1 Jan 2008
Mateuca Raluca A, Roelants Mathieu, Iarmarcovai Gwenaelle, Aka Peter V, Godderis Lode, Tremp Annie, Bonassi Stefano, Fenech Michael, Bergé-Lefranc Jean-Louis, Kirsch-Volders Micheline
Abstract excerpt
A pooled analysis of five biomonitoring studies was performed to assess the influence of hOGG1(326), XRCC1(399) and XRCC3(241) gene polymorphisms on micronuclei (MN) frequency in human peripheral blood lymphocytes, as measured by the ex vivo/in vitro cytokinesis-block micronucleus (CBMN) assay. Each study addressed a type of occupational exposure potentially able to induce DNA strand breakage (styrene, ionising...
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