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Article

Association of genetic polymorphisms in ERCC1 and ERCC2/XPD with risk of chronic benzene poisoning in a Chinese occupational population.

Mutation research - 18 Feb 2013

Xiao Sha, Gao Lin, Liu Yanhua, Yu Tao, Jin Cuihong, Pan Liang, Zhu Guolian, Lu Xiaobo

Abstract excerpt

DNA damage induced by benzene and its metabolites is thought of as an important mechanism underlying benzene genotoxicity in chronic benzene poisoning (CBP). Therefore, genetic variation in DNA repair genes may contribute to susceptibility to CBP in the exposed population. Since benzene-induced DNA damages include DNA adducts, we hypothesized that the polymorphisms of ERCC1 (Excision repair cross complementation...

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Source

Identifiers

PMID: 23147699
DOI: 10.1016/j.mrgentox.2012.11.002

Genes

ERCC1
ERCC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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